- Baseball: Bloomfield at Woodland
- Baseball: Century (Ullin, Ill.) at Saxony Lutheran
- Baseball: Chaffee at Scott City
- Baseball: Delta at Gideon
- Baseball: Doniphan at Puxico
- Baseball: Meadow Heights at Leopold
- Baseball: Naylor at Southland
- Baseball: Oak Ridge at Perryville, Canceled
- Baseball: St. Vincent at DeSoto
- Baseball: Twin Rivers at Kelly
- Boys Tennis: Notre Dame at Sikeston
- Boys Tennis: Poplar Bluff at Cape Central, Canceled
- Girls Soccer: Kelly at Fredericktown
- Girls Soccer: Saxony Lutheran at North County
- Girls Soccer: Sikeston at Poplar Bluff, PPD
- Girls Soccer: St. Vincent at Perryville, PPD
- Softball: (7) Delta (Deering) vs (2) New Madrid Co. Central at C1D1 Quarterfinal @NMCC
- Softball: (6) Cooter vs (3) North Pemiscot at C1D1 Quarterfinal @NMCC
- Softball: (5) South Pemiscot vs (4) Caruthersville at C1D1 Quarterfinal @NMCC
- Softball: (5) Gideon vs (4) Campbell at C1D2 Quarterfinal @Kennett
- Softball: (6) Holcomb vs (3) Southland at C1D2 Quarterfinal @Kennett
- Softball: (7) Bloomfield vs (2) Bernie at C1D3 Quarterfinal @Malden
- Softball: (5) Dexter vs (4) Charleston at C1D3 Quarterfinal @Malden
- Softball: (8) Richland (Essex) vs (1) Malden at C1D3 Quarterfinal @Malden
- Softball: (6) Risco vs (3) Puxico at C1D3 Quarterfinal @Malden
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